Science Jobs

Sr. Scientist, Protein Biochemistry

DISCOVERY RESEARCH (SCIENCE)
  • Job ID: 19774
  • Direct Hire
  • MA
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Sr. Scientist, Protein Biochemistry
Location: Boston, Massachusetts  

  HireMinds is representing a clinical-stage biopharmaceutical client that is leading the way in developing biologics. Our clients approach allows them to selectively engage and modulate disease-specific T cells, aiming to transform the treatment landscape for cancer, autoimmune, and inflammatory diseases. Located in an exciting new lab space in Boston’s vibrant life sciences corridor they have a collaborative team with hands-on leadership that is present and invested in the team’s success. Reach out to HireMinds Biotech team or apply today to learn more! 

You’ll Be Responsible For: 

  • In this role you’ll work as a Scientist or Senior Scientist in a Protein Discovery team and bring your hands-on skill in protein purification and work in protein characterization. 
  • Work on mammalian expression of products including: engineered Fc-fusion, recombinant proteins 
  • Perform protein purification with affinity, ion-exchange (IEX), and size-exclusion chromatography (SEC).  
  • Progress programs into downstream testing in Quality Control and characterization utilizing methods including: SE-HPLC, SDS-PAGE, UV-Vis spectroscopy, and ELISA.  
  • Design and execute buffer screens and assays to optimize formulations of protein therapeutics. 
  • Bring experience with optimization of protein conjugation and purification processes  
  • Present your findings through well-structured documentation and engaging oral presentations to peers and management teams. 
  • Manage routine maintenance of instrumentation vital to protein biochemistry and collaborate with vendors when necessary. 

You’ll Bring With You: 

  • B.S. or M.S. in pharmaceutical, biological, or chemical sciences with 7–8 years of industry experience, or  
  • Ph.D. in a relevant field with 2 years of industrial experience in Biotech or Biopharma.  
  • Strong hands-on experience in protein purification and a solid grasp of protein biochemistry.  
  • Hands-on experience with instrumentation, including AKTA systems and bioanalytical techniques: HPLC, DSC, SEC-MALS, DSF. 
  • Proven ability to design and carry out biochemical or biological assays.  
  • Previous experience with protein conjugation chemistry is preferred. 

This position offers an extraordinary chance for protein biochemists eager to make a significant impact on drug discovery while expanding their professional skills in a collaborative and innovative setting. Become part of our clients mission to redefine treatment options for patients.